> Projection of a NIRS channel on a brain surface
Projection of a NIRS channel on a brain surface
When analyzing the data in our concurrent NIRS-fMRI study, we are particularly interested in how the NIRS signals were correlated to the fMRI signal. To answer the question we need to create an ROI (region of interest) in brain which is directly underneath the NIRS channel (which is on the skull). So a projection of the NIRS channel on the brain surface is necessary.
It might be easy if the brain were a perfect sphere, or at least doable if it is smooth. But brain surface is anything but smooth. What we did is:
- Create a brain surface mask. This is easy using BET (http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/BET)
- Loop over all voxels on the surface, calculate the distance between the NIRS channel (point A) and the voxel
- Find the voxel which is closest to the NIRS channel (It is point B in the figure below)
Projection of NIRS channel on brain surface
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About the author:
Xu Cui is a human brain research scientist in Stanford University. He lives in the Bay Area in the United States. He is also the founder of Stork (smart publication alert app), PaperBox and BizGenius.
He was born in He'nan province, China. He received education in Beijing University(BS), University of Tennessee (Knoxville) (MS), Baylor College of Medicine (PhD) and Stanford University (PostDoc). Read more ...